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Preheat oven to 400 degrees.
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In a deep dish, mix flour, cayenne pepper, paprika, black pepper and salt together.
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In a bowl, whisk whole-grain mustard, yellow mustard, honey, garlic and lemon juice. Set aside.
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In a food processor, crush 1 1/2 cups of small pretzels. Combine pretzels in a shallow dish with the panko bread crumbs.
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Dredge chicken in the flour, then the honey-mustard and then the pretzel breading.
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Place strips on a lined baking sheet.
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Spray each piece of chicken with non-stick cooking spray.
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Bake for 25 minutes or until chicken is done.